Compounding

Oral Liquids (Suspensions, Syrups, Elixers)

Oral LiquidsThis is a popular dosage form in pediatrics, geriatrics, and for those who have difficulty swallowing solid dosage forms. Due to the fact that many drug products are not commercially available as oral liquids, the compounding pharmacist is often asked to compound oral liquid dosage forms. A variety of dosages and flavors can often be prepared.

 

How do we compound your liquid medication?

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Choosing a Formulation

Depending on the drug being compounded, the pharmacist will choose a specific form of liquid to compound such as a suspension, syrup, or elixer. Their selection will take into consideration such things as whether the drug is soluble and stable in the chosen liquid, ease of pouring, taste, and resistance to microbial attack.

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Measuring the Ingredients

Next, the drug as well as any other ingredients (ex. suspending agents, flavors, preservatives, the liquid vehicle) will be weighed out accurately on a prescription weigh scale for powders or measured in a graduated cylinder for liquids.

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Mixing the Ingredients

Once all the ingredients are ready, they will be gradually mixed, usually first into a thick paste, and as more liquid is added, eventually into the final volume of liquid product.

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Packaging

The final product is packaged into plastic or glass amber prescription bottles and is labeled appropriately for the patient it was compounded for. Lot number and expiry date are noted and any special storage instructions are included. If necessary, a variety of special adaptable caps can be attached to the bottle to allow accurate measurement of the dosage directly into an oral syringe for the patient.